San Francisco 49ers
Cumulative Score
Patriots
121
49ers
119
Average Score
Patriots
24
49ers
24
Patriots vs 49ers
3 - 2
| Score | ||||||||
|---|---|---|---|---|---|---|---|---|
| Game | Pats | Opp | Location | Date | Coach | O/U | Vegas | |
| 2004 Week 17 | 21 | 7 | Home | January 2, 2005 | Dennis Erickson | 37.0 | -13.0 | |
| 2008 Week 5 | 30 | 21 | Away | October 5, 2008 | Mike Nolan | 41.0 | -3.0 | |
| 2012 Week 15 | 34 | 41 | Home | December 16, 2012 | Jim Harbaugh | 47.5 | -5.0 | |
| 2016 Week 11 | 30 | 17 | Away | November 20, 2016 | Chip Kelly | 51.5 | -10.5 | |
| 2020 Week 7 | 6 | 33 | Home | October 25, 2020 | Kyle Shanahan | 44.5 | -3.0 | |